TY - JOUR AU - Luisier, Jean-Luc AU - Veyrand, Julien AU - Piantini, Umberto PY - 2007/07/25 Y2 - 2024/03/29 TI - Characterisation and Simple Synthesis of S-[3-Hydroxy-1-propylpropyl]-L-cysteine: FH - HES JF - CHIMIA JA - Chimia VL - 61 IS - 7-8 SE - Columns, Conference Reports DO - 10.2533/chimia.2007.533 UR - https://www.chimia.ch/chimia/article/view/2007_533 SP - 533 AB - A convenient new synthetic approach has been established to prepare S-[3-hydroxy-1-propylpropyl]-L-cysteine 4 by Michael-addition of enantiomerically pure L-cysteine to (2E)-2-hexenoic acid ethyl ester followed by selective reduction of the ester function with sodium trimethoxyborohydride. All compounds were obtained as a diastereomeric mixture in good yields and their structures were determined by NMR and MS analyses. ER -