iMatrixSpray: A Free and Open Source Sample Preparation Device for Mass Spectrometric Imaging


  • Markus Stoeckli Novartis Institutes for Biomedical Research, WSJ-155.2.27, Novartis Campus, CH-4056 Basel, Switzerland
  • Dieter Staab
  • Michael Wetzel
  • Matthias Brechbuehl



Maldi, Maldi msi, Mass spectrometric imaging, Matrix deposition, Sample preparation


A device was built for matrix deposition in mass spectrometric imaging. This spray-type instrument requires no user interaction other than providing the spray solution and selecting the pre-defined or custom-built method. Robustness was achieved by utilizing a delta-robotics design in combination with a simple liquid system. All the information describing the systems is provided as open source and hardware and the design is therefore suitable for wide distribution and adaption by the scientific community.




How to Cite

M. Stoeckli, D. Staab, M. Wetzel, M. Brechbuehl, Chimia 2014, 68, 146, DOI: 10.2533/chimia.2014.146.