CHIMIA

This special issue of CHIMIA covers a selection of topics that were presented in the scientific sessions of the 2^nd International Symposium on Chemical Biology (EFMC-ISCB) that covered mechanistic insights into cell-targeted therapeutics, advancements in probe design and platform technologies for uncovering biological pathways and drug target space, the discovery and application of peptide macrocycles, proximity-based chemical biology for drug discovery, advances in activity-based protein profiling and high-throughput chemical proteomics, chemical biology of chromatin and the epitranscriptome, as well as new modalities and specific strategies for RNA modification and degradation.