Neuere Aspekte in der Chemie der Indolalkaloide

Abstract

Recent experiments in the indole-field concerning biogenetic patterned transformations are reviewed. Cyclisations of oxindole-iminoethers failed to yield the Strychnos-ring-structure, while the transformations of a ring-open Corynanthe-type intermediate into the Yohimbin skeleton was achieved via an enamine. An autoxidative route from an indole-compound to the ring-structure of Camptothecin as well as an easy way to synthesize its chromophore is reported.