On-line Festphasenextraktion (SPE) für die HPLC

On-line Solid Phase Extraction for LC Analysis

Authors

  • Heinrich Obrist

DOI:

https://doi.org/10.2533/chimia.2001.46

Keywords:

Environmental analysis, Food analysis, On-line solid phase extraction, Pharmaceutical analysis, Sample clean-up

Abstract

Solid Phase Extraction (SPE) has rapidly evolved to become one of the most popular methods for sample clean-up today. Based on well-known chromatographic principles, SPE is easily performed, typically provides superior results, and will continue to replace traditional extraction techniques. SPE can be automated using robotic type sample processors; however, for SPE followed by LC or LC/MS, there is a much more efficient alternative and offers ruggedness, excellent precision and high sample throughput. With the PROSPEKT-System, the purified analytes elute directly from the SPE column onto the analytical column for LC analysis, eliminating off-line sample transfer including eluate collection, evaporation, reconstituation and injection.

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Published

2001-02-28