Nonnatural Phospholipids: Probing Nature's Modular Platform

Authors

  • Andreas Zumbuehl

DOI:

https://doi.org/10.2533/chimia.2009.63

Keywords:

Biophysics, Membrane probes, Nonnatural phospholipids

Abstract

Life as we know it would not be possible without a cellular membrane, without a separation between two compartments. This plasma membrane, however, remains a difficult object to study directly. The synthesis of nonnatural phospholipids thus provides valuable probes for experiments at the membrane-level and integrates organic chemistry with basic biophysics and biology. A few of the concepts are highlighted in this brief overview.

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Published

2009-02-25