Radical Carbon–Carbon Bond Formations Enabled by Visible Light Active Photocatalysts

Authors

  • Carl-Johan Wallentin
  • John D. Nguyen
  • Corey R. J. Stephenson Department of Chemistry, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA

DOI:

https://doi.org/10.2533/chimia.2012.394

Keywords:

Carbon-carbon bond, Flow reactor, Photocatalysis, Radical, Visible light

Abstract

This mini-review highlights the Stephenson group's contribution to the field of photoredox catalysis with emphasis on carbon–carbon bond formation. The realization of photoredox mediated reductive dehalogenation initiated investigations toward both intra- and intermolecular coupling reactions. These reactions commenced via visible light-mediated reduction of activated halogens to give carbon-centered radicals that were subsequently involved in carbon–carbon bond forming transformations. The developed protocols using Ru and Ir based polypyridyl complexes as photoredox catalysts were further tuned to efficiently catalyze overall redox neutral atom transfer radical addition reactions. Most recently, a simplistic flow reactor technique has been utilized to affect a broad scope of photocatalytic transformations with significant enhancement in reaction efficiency.

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Published

2012-06-27

How to Cite

[1]
C.-J. Wallentin, J. D. Nguyen, C. R. J. Stephenson, Chimia 2012, 66, 394, DOI: 10.2533/chimia.2012.394.

Issue

Section

Scientific Articles