Recent Developments in the Field of Enzyme Inhibitors

Abstract

The present article summarizes the recent developments in the design and use of enzyme inactivators as put forward on the occasion of the joint meeting on “Enzyme Inhibitors” held under the auspices of the Swiss Chemical Society and the Division of Medicinal Chemistry of the German Chemical Society at Sandoz headquarters in Basel, March. 1980. In total 25 papers were presented by investigators from industrial and university laboratories. The two day meeting once again showed that the bridge in science and technology between industry and university is important and of mutual benefit. It finely demonstrated how scientists of both groups can profit from each other. Those carrying out applied research were confronted with the latest ideas and developments pertaining the design of highly specific enzyme inhibitors; those doing basic research again became aware of the long road a bioactive compound has to travel if at all it becomes marketable.