Rapid Synthesis of Bradykinin in Solution

Authors

  • Hanspeter Rolli Institute for Clinical Immunology, Inselspital, 3010 Bern; Institute for Organic Chemistry, Freiestrasse 3, 3012 Bern
  • Conrad H. Schneider Institute for Clinical Immunology, Inselspital, 3010 Bern; Institute for Organic Chemistry, Freiestrasse 3, 3012 Bern

DOI:

https://doi.org/10.2533/chimia.1981.403

Abstract

Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a model. In one synthesis, intermediate purification by liquid-liquid extraction was carried out after each completed elongation, in the other, new variant, the extractions were performed after the deprotection steps. If not hampered by technical difficulties the second variant is more efficient.

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Published

1981-10-31

Issue

Vol. 35 No. 10 (1981): Forschung/Research

Section

Kurze Mitteilungen

License

Copyright (c) 1981 Hanspeter Rolli

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
H. Rolli, C. H. Schneider, Chimia 1981, 35, 403, DOI: 10.2533/chimia.1981.403.