Consideration of Solid-Phase Synthesis with Reference to Quinolone Antibiotics
AbstractThe general utility of solid-phase synthesis for creating libraries of compounds will be discussed with particular reference paid to the development of a solid-phase organic synthetic route to quinolones. Using the DIVERSOMER® technology a library of quinolones have been prepared, purified and analyzed. Additionally, the issue of resin impurities and by-products will be discussed.
How to Cite
A. A. Macdonald, S. H. DeWitt, R. Ramageu, Chimia 1996, 50, 266, DOI: 10.2533/chimia.1996.266.
Copyright (c) 1996 Swiss Chemical Society
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