About Bases and Superbases
AbstractButyllithium requires activation in order to become capable of abstracting a proton from weakly acidic hydrocarbons like cyclopropanes, simple olefins, or arenes. The addition of a stoichiometric amount of potassium tert-butoxide is a most effective means of enhancing the rate of a hydrogen/metal exchange process. The superbasic alkyllithium/potassium alcoholate mixtures are endowed not only with an unsurpassed reactivity but also with a surprisingly high selectivity as evidenced by a series of optionally site-selective arene metalations.
How to Cite
F. Mongin, R. Maggi, M. Schlosser, Chimia 1996, 50, 650, DOI: 10.2533/chimia.1996.650.
Copyright (c) 1996 Swiss Chemical Society
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.