Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst

Authors

  • Manfred T. Reetz
  • Klaus Schimossek

DOI:

https://doi.org/10.2533/chimia.1996.668

Abstract

The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%).

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Published

1996-12-18

How to Cite

[1]
M. T. Reetz, K. Schimossek, Chimia 1996, 50, 668, DOI: 10.2533/chimia.1996.668.

Issue

Vol. 50 No. 12 (1996): Chemistry in Lausanne

Section

Note

License

Copyright (c) 1996 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.