Excursions of Synthetic Organic Chemists to the World of Oligomers and Polymers
Keywords:Dendritic cross-linkers, Oligo-(3-hydroxybutanoates), Beta-peptides, Polymer-bound chiralligands, Secondary structures
AbstractThe activities of a group devoted to organic synthesis in the field of polymer and oligomer chemistry have led to new types of dendritic cross-linking compounds for the polymerization of styrene to give high-quality materials. In addition the synthesis of uniform ('monodisperse'), high-molecular weight oligomers of 3-hydroxybutanoic acid provided samples for investigations to prove the hypothesis that polyhydroxybutyrates are natural ion-channel components in living organisms. Oligomers of ?-amino acids were prepared and have been shown to form all the secondary structures known from natural peptides and proteins (composed of ?-amino acids), i.e. helices, pleated sheets, turns, hair pins and stacks with properties differing fundamentally from those of the natural analogs.
How to Cite
D. Seebach, A. K. Beck, M. Rueping, J. V. Schreiber, H. Sellner, Chimia 2001, 55, 98, DOI: 10.2533/chimia.2001.98.
Copyright (c) 2001 Swiss Chemical Society
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