Bioorganic Chemistry of Rigid-Rod Molecules: Adventures with p-Oligophenyls
Keywords:Antibiotics, Beta-barrels, Enzyme mimics, Ion channels, Molecular recognition, Sensors
AbstractStudies on the usefulness of rigid-rod molecules to address pertinent questions of biological relevance are summarized. Emphasis is placed on (a) the supramolecular functional plasticity of p-octiphenyl ?-barrels expressed in molecular recognition (adaptable synthetic hosts), molecular translocation (adaptable synthetic ion channels) and molecular transformation (esterases, RNases), (b) molecular recognition of polarized membranes by rigid push-pull rods, as well as (c) the synthetic organic chemistry of rigid-rod molecules.
How to Cite
Y. Baudry, B. Baumeister, G. Das, D. Gerard, S. Matile, N. Sakai, A. Som, N. Sordé, P. Talukdar, Chimia 2002, 56, 667, DOI: 10.2533/000942902777679948.
Copyright (c) 2002 Swiss Chemical Society
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