Development of Organometallic Ruthenium(II) Anticancer (RAPTA) Drugs

Authors

  • Wee Han Ang

DOI:

https://doi.org/10.2533/chimia.2007.140

Keywords:

Anticancer drugs, Antitumour, Chemotherapy, Metallopharmaceuticals, Ruthenium

Abstract

The systematic development of the RAPTA family of organometallic ruthenium(II) anticancer drugs containing a monodentate 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1]decane (pta) ligand and a ?6-arene ligand is described.

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Published

2007-04-25