Artificial Metalloenzymes for Enantioselective Catalysis Based on the Biotin-Avidin Technology

Authors

  • Jincheng Mao
  • Thomas R. Ward

DOI:

https://doi.org/10.2533/chimia.2008.956

Keywords:

Artificial metalloenzymes, Asymmetric catalysis, Biotin-(strept)avidin technology, Enantioselectivity

Abstract

Artificial metalloenzymes, based on the incorporation of a biotinylated catalytically active organometallic moiety within streptavidin, offer an attractive alternative to homogeneous, heterogeneous and enzymatic catalysis. In this account, we outline our recent results and implications in the developments of such artificial metalloenzymes for various asymmetric transformations, including hydrogenation, transfer hydrogenation, allylic alkylation and sulfoxidation.

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Published

2008-12-17

How to Cite

[1]
J. Mao, T. R. Ward, Chimia 2008, 62, 956, DOI: 10.2533/chimia.2008.956.

Issue

Section

Scientific Articles