Fluorescence Sensors for Lithium Ions and Small Peptides

Authors

  • Sébastien Rochat Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, CH-1015 Lausanne
  • Kay Severin

DOI:

https://doi.org/10.2533/chimia.2010.150

Keywords:

Fluorescence spectroscopy, Indicator displacement assay, Lithium, Peptide, Sensor

Abstract

Simple but powerful chemosensors were developed by taking advantage of self-assembly processes. First, we will describe a turn-on fluorescent sensor for the pharmacologically important lithium ion. The sensor can be used in purely aqueous solution, and it displays a very high selectivity for lithium over sodium and magnesium ions. It is based on a metallacrown receptor unit, which can be assembled in situ from simple building blocks. Furthermore, we will describe a cross-reactive sensor array for the detection of small peptides. The individual sensors of the array are formed by mixing metal complexes with fluorescent dyes.

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Published

2010-03-31

How to Cite

[1]
S. Rochat, K. Severin, Chimia 2010, 64, 150, DOI: 10.2533/chimia.2010.150.