Some Aspects of the Radical Chemistry of Xanthates
Keywords:Block copolymers, Carbon-carbon formation, Heterocycles, Radical additions, Xanthates
AbstractXanthates and related thiocarbonylthio derivatives have proved to be exceedingly useful substrates for both inter- and intra- molecular radical additions. The intermolecular addition to unactivated alkenes, in particular, provides tremendous opportunities for synthesis: various functional groups can be brought together under mild, neutral conditions. Since the adduct is also a xanthate, iteration allows the formation of block polymers through a controlled radical polymerisation (the RAFT/MADIX technology). Also of some importance is the access to highly substituted aromatic and heteroaromatic derivatives.
How to Cite
B. Quiclet-Sire, S. Z. Zard, Chimia 2012, 66, 404, DOI: 10.2533/chimia.2012.404.
Copyright (c) 2012 Swiss Chemical Society
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