Synthesis of Nanometer-sized Rod–Coil Block Copolymers

Hannah M. König; Andreas F. M. Kilbinger

doi:10.2533/chimia.2013.788

Synthesis of Nanometer-sized Rod–Coil Block Copolymers

Authors

Hannah M. König Department of Chemistry University of Fribourg Chemin du Musée 9 CH-1700 Fribourg, Switzerland
Andreas F. M. Kilbinger Department of Chemistry University of Fribourg Chemin du Musée 9 CH-1700 Fribourg, Switzerland. andreas.kilbinger@unifr.ch

DOI:

https://doi.org/10.2533/chimia.2013.788

Keywords:

Aramide, Block copolymers, Oligomers, Self-assembly, Solid-supported synthesis

Abstract

We present the solid-supported synthesis of a linear rigid rod-like tetradeca(p-benzamide) nanorod as well as a pentadeca( p -benzamide) nanorod carrying an amide N-hexyl side chain at the center of the rod (on the 8th amino acid of the molecule). These nanorods were conjugated with solubilizing poly(ethylene glycol) chains and their solution aggregation was investigated. Both rod–coil block copolymers form soluble aggregates even in polar aprotic solvents such as DMF and DMSO. We show that sequence-controlled nanometer-sized shape persistent aramide scaffolds can readily be prepared using solid-supported synthesis.