Cascades, Catalysis and Chiral Ligand Control with SmI₂; The Rebirth of a Reagent
DOI:
https://doi.org/10.2533/chimia.2020.18PMID:
32200782Keywords:
Enantioselective desymmetrisation, Radical cascade, Radical relay catalysis, Samarium diiodideAbstract
This review focuses on recent developments from our laboratory in the field of radical reactions mediated by the archetypal reductive single electron transfer (SET) reagent, SmI2. Namely, we have expanded the scope of reducible carbonyl moieties to esters and amides and have exploited the resultant ketyl radicals in radical cascade reactions that generate unprecedented scaffolds. Moreover, we have taken the first steps to address the long-standing challenges of catalysis and chiral ligand control associated with the reagent.
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Published
2020-02-26
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Scientific Articles
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Copyright (c) 2020 Áron Péter, David J. Procter
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
[1]
Chimia 2020, 74, 18, DOI: 10.2533/chimia.2020.18.