How Technical Innovations May Help to Prevent Drug Shortages in Switzerland
Keywords:Automation of chemical synthesis, Drug shortage, Micropellet formulation, On-demand production, Personalized healthcare
In this work, we investigated the technical feasibility of 'on-demand' production of selected drugs to cover their demand for a time window of 90 days. We focused on two sub-processes 'automated chemical synthesis' and 'formulation in micropellets' to enable personalized dosing. The production of drugs 'on-demand' is challenging, important, but also attractive. Switzerland could thus gain access to an additional instrument for increasing resilience for supply-critical drugs. The biggest challenge in the case study presented here is the scalability of automated chemical synthesis and the application range of micropellet formulations.
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Copyright (c) 2023 Daniel Gygax, Kaspar Eigenmann, Christian Suter, Marianne Hürzeler, Ahmed Mahmoud, Johannes Mosbacher, Norbert Pöllinger
This work is licensed under a Creative Commons Attribution 4.0 International License.