Single-Use Technology Today – A Cornucopia of Applications
DOI:
https://doi.org/10.2533/chimia.2025.312PMID:
40439610Keywords:
Biotherapeutics, Process intensification and continuous manufacturing, Single-use facilities, Single-use systems and process platformsAbstract
Whether for classic biologics or advanced therapy medicinal products (ATMPs), laboratory applications, small-scale or large-scale productions, single-use technology (SUT), and its associated consumables are used everywhere. The advantages of deploying SUTs are well known. Wherever a single-use solution is available, it is tested and ultimately used. Based on milestones in the development of single-use systems and single-use platform technologies, this article provides an up-to-date overview of products available on the market and their manufacturers/suppliers. It also discusses process examples with SUTs, design options and configurations of single-use facilities and Switzerland’s pioneering role in the development and implementation of SUTs. In addition, the authors show that SUT has already been established beyond the biopharmaceutical sector.
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Copyright (c) 2025 Diego R. Schmidhalter, Dieter Eibl, Regine Eibl

This work is licensed under a Creative Commons Attribution 4.0 International License.