Single-Use Technology Today – A Cornucopia of Applications

Authors

  • Diego R. Schmidhalter Alpha Lyncis SA, Rue Charles-Clos Olsommer 1, CH-3968 Veyras, Switzerland
  • Dieter Eibl Alpha Lyncis SA, Rue Charles-Clos Olsommer 1, CH-3968 Veyras, Switzerland
  • Regine Eibl Alpha Lyncis SA, Rue Charles-Clos Olsommer 1, CH-3968 Veyras, Switzerland

DOI:

https://doi.org/10.2533/chimia.2025.312

PMID:

40439610

Keywords:

Biotherapeutics, Process intensification and continuous manufacturing, Single-use facilities, Single-use systems and process platforms

Abstract

Whether for classic biologics or advanced therapy medicinal products (ATMPs), laboratory applications, small-scale or large-scale productions, single-use technology (SUT), and its associated consumables are used everywhere. The advantages of deploying SUTs are well known. Wherever a single-use solution is available, it is tested and ultimately used. Based on milestones in the development of single-use systems and single-use platform technologies, this article provides an up-to-date overview of products available on the market and their manufacturers/suppliers. It also discusses process examples with SUTs, design options and configurations of single-use facilities and Switzerland’s pioneering role in the development and implementation of SUTs. In addition, the authors show that SUT has already been established beyond the biopharmaceutical sector.

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Published

2025-05-28

Issue

Section

Scientific Articles

How to Cite

[1]
D. R. Schmidhalter, D. Eibl, R. Eibl, Chimia 2025, 79, 312, DOI: 10.2533/chimia.2025.312.