Industrializing Biocatalysis

Authors

  • Katrin Hecht Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, CH-8820 Wädenswil, Switzerland
  • Rebecca Buller Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, CH-8820 Wädenswil, Switzerland

DOI:

https://doi.org/10.2533/chimia.2025.522

PMID:

40838405

Keywords:

Biocatalysis, Bioinformatics, Enzyme discovery, Enzyme engineering, Late-stage functionalization

Abstract

Biocatalysis leverages enzymes, nature’s catalysts, to enhance essential steps in chemical synthesis, thereby promoting more sustainable and efficient processes. Enzymes, macromolecular proteins, catalyze reactions with precision and efficiency in all living organisms. These biocatalysts have been honed over millenia for their specific roles within a biological system; however, they can be effectively reengineered to address novel challenges through recent advancements in molecular biology and bioinformatics. In this review, we present selected enzyme sourcing and engineering examples from our laboratory demonstrating the transition of enzymatic processes from academic research to application in Swiss industries.

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Published

2025-08-20