Homogeneous Ruthenium-Catalyzed Carbonyl Groups Selective Hydrogenation Towards F&F Industrial Applications

Abstract

Over the past decades, dsm-firmenich has devoted substantial efforts towards continuous perfumery ingredients and production sustainability improvement through the implementation of green chemistry principles, generally leading to safer, more efficient but also cost-effective industrial chemical processes. Among the numerous examples of innovative homogeneous and heterogeneous catalytic methodologies that have been implemented over the years, we herein provide some insights into more than 20 years of discovery and development in selective carbonyl group hydrogenation reactions for the replacement of waste generating stoichiometric methods, allowing highly efficient access to a large variety of unsaturated alcohols as widespread synthetic intermediates or final ingredients in the Flavor and Fragrance (F&F) industry.