Neuere Anwendungen der magnetischen Kernresonanz-Spektroskopie

Abstract

Nuclear magnetic resonance (NMR) has taken a firm place among the spectroscopic methods. It has become a rapid and powerful aid in the elucidation of unknown structures and stereochemical questions. This lecture will be mainly concerned with high-resolution proton magnetic resonance which has been employed in the greater part of the work in this field.
The physical principles underlying NMR will be dealt with briefly and the experimental methods explained. The several causes of the chemical shift (electronegativity, anisotropic susceptibility and electric dipole moment of substituents, hybridization) as well as the origin, interpretation, nomenclature and angular dependence of spin-spin splittings will be discussed and supported with typical examples. Finally, it will be shown how these criteria, together with signal integration and proton-proton spin decoupling may be applied in the unravelling of more complex spectra.