Keywords:Artificial ribonucleases, Lanthanide complexes, Oligonucleotide, Rna, Rna cleavage
AbstractChemically modified oligonucleotides serve as tools in fundamental research as diagnostic reagents and pharmaceutical compounds. Various chemical groups can nowadays be linked to oligonucleotides, In particular, synthetic constructs of oligonucleotides and lanthanide complexes can serve as artificial ribonucleases. In this paper, some applications of modified oligonucleotides originating from our research efforts directed at the development of artificial ribonucleases are summarized.
How to Cite
R. Häner, Chimia 2001, 55, 1035, DOI: 10.2533/chimia.2001.1035.
Copyright (c) 2001 Swiss Chemical Society
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