Towards the Directed Evolution of Hybrid Catalysts
Keywords:Chemical modification, Directed evolution, Enzymes, Hybrid catalysts, Transition metal catalysis
AbstractThe first step in applying the recently proposed concept concerning the application of directed evolution to the creation of selective hybrid catalysts is described, specifically the covalent attachment of Mn-salen moieties and of Cu-, Pd-, and Rh-complexes of dipyridine derivatives as well as the implantation of a diphosphine moiety in a protein, future steps being cycles of mutagenesis/screening.
How to Cite
M. T. Reetz, M. Rentzsch, A. Pletsch, M. Maywald, Chimia 2002, 56, 721, DOI: 10.2533/000942902777679920.
Copyright (c) 2002 Swiss Chemical Society
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