Towards the Directed Evolution of Hybrid Catalysts

Authors

  • Manfred T. Reetz
  • Martin Rentzsch
  • Andreas Pletsch
  • Matthias Maywald

DOI:

https://doi.org/10.2533/000942902777679920

Keywords:

Chemical modification, Directed evolution, Enzymes, Hybrid catalysts, Transition metal catalysis

Abstract

The first step in applying the recently proposed concept concerning the application of directed evolution to the creation of selective hybrid catalysts is described, specifically the covalent attachment of Mn-salen moieties and of Cu-, Pd-, and Rh-complexes of dipyridine derivatives as well as the implantation of a diphosphine moiety in a protein, future steps being cycles of mutagenesis/screening.

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Published

2002-12-01

How to Cite

[1]
M. T. Reetz, M. Rentzsch, A. Pletsch, M. Maywald, Chimia 2002, 56, 721, DOI: 10.2533/000942902777679920.

Issue

Vol. 56 No. 12 (2002): Chemistry at the University of Geneva

Section

Note

License

Copyright (c) 2002 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.