Mass Spectrometry in Proteomics: Technologies, Methods, and Research Applications for the Life Sciences

Authors

  • Paolo Nanni Functional Genomics Center Zurich, University of Zurich / ETH Zurich https://orcid.org/0000-0001-8429-3557
  • Peter Gehrig Functional Genomics Center Zurich, University of Zurich / ETH Zurich
  • Ralph Schlapbach Functional Genomics Center Zurich, University of Zurich / ETH Zurich

DOI:

https://doi.org/10.2533/chimia.2022.73

PMID:

38069752

Keywords:

Core facilities, Life sciences, Mass spectrometry, Protein analysis, Proteomics

Abstract

Mass spectrometry is a powerful tool in the hand of life science researchers, who constantly develop and apply new methods for the investigation of biomolecules, such as proteins, peptides, metabolites, lipids, and glycans. In this review, we will discuss the importance of mass spectrometry for the life science sector, with a special focus on the most relevant current applications in the field of proteomics. Moreover, we will comment on the factors that research groups should consider when setting up a mass spectrometry laboratory, and on the fundamental role played by academic core facilities and industrial service providers.

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Published

2022-02-23

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