Raman Optical Activity (ROA) as an Emerging Standard in Molecular Chirality Measurements – A Perspective

Abstract

Raman Optical Activity (ROA) is emerging as a powerful analytical tool for the characterization of molecular chirality, offering complementary capabilities to established chiroptical and crystallographic methods. In particular, its ability to probe molecules in solution and across a wide range of chemical classes makes it increasingly relevant for modern chemical and pharmaceutical research. This perspective highlights recent developments, practical considerations, and future opportunities.