Selective Release of Technetium Complexes from a Solid Phase due to C–N Bond Cleavage upon Metal Coordination
Keywords:Cleavage reactions, Radiopharmaceuticals, Solid-phase synthesis, Technetium
AbstractA new method for 99mTc-labeling using solid-phase technology is described. It allows the separation of unlabeled from labeled bioactive molecules by simple filtration. The procedure is based on a site-specific C–N bond cleavage reaction initiated by the formation of [TcI(CO)3L]-complexes.
How to Cite
S. Mundwiler, L. Candreia, R. Alberto, Chimia 2003, 57, 193, DOI: 10.2533/000942903777679514.
Copyright (c) 2003 Swiss Chemical Society
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