Mechanistic Views on First-row Earth-Abundant Transition Metal Catalyzed Ullmann-type O-Arylation Reactions

Authors

  • Parvathi Santhoshkumar Department of Chemistry, CMS College Kottayam (Autonomous), Kerala,India
  • C. Rajalakshmi Department of Chemistry, CMS College Kottayam(Mahatma Gandhi University) Kerala, India https://orcid.org/0000-0003-2491-5945
  • Lydia Elizabeth Mathews Department of Chemistry, CMS College Kottayam(Mahatma Gandhi University) Kerala, India
  • Rehin Sulay Department of Chemistry, CMS College Kottayam(Mahatma Gandhi University) Kerala, India
  • Vibin Ipe Thomas Department of Chemistry, CMS College Kottayam(Mahatma Gandhi University) Kerala, India https://orcid.org/0000-0003-3928-2319

DOI:

https://doi.org/10.2533/chimia.2023.246

PMID:

38047805

Keywords:

Density Functional Theory, Mechanistic studies, O-arylation, Transition-metal catalysis

Abstract

Transition metal-catalyzed reactions have attracted much attention in synthetic organic chemistry due to their important role in the formation of C-heteroatom bonds. Ullmann coupling has risen in prominence in recent decades owing to its utilization in the synthesis of biaryl ethers found in a wide range of natural products together with biologically essential molecules, including antibiotics and major industrial polymers. In this article we provide the current understanding of the theoretical aspects of the underlying mechanism of the Ullmann-type O-arylation reaction.

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Published

2023-04-26

How to Cite

[1]
P. Santhoshkumar, C. Rajalakshmi, L. E. Mathews, R. Sulay, V. I. Thomas, Chimia 2023, 77, 246, DOI: 10.2533/chimia.2023.246.