Vol. 50 No. 9 (1996): Biotechnology for Industrial Production of Fine Chemicals

Published: 1996-09-25

Editorial

Biotechnology for Industrial Production of Fine Chemicals Editorial

H.P. Meyer, H.G. Leuenberger

407
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Scientific Articles

Structure, Function, and Application of Microbial Lactonases

Sakayu Shimizu, Michihiko Kataoka

409
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Development of a Fermentation Process for the Manufacture of Riboflavin

Adolphus P.G.M. van Loon, Hans-Peter Hohmann, Werner Bretzel, Markus Hümbelin, Magdalena Pfister

410
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Bioprocess Technologies Depending on the Molecular Structure of Pharmaceutical Products

Berthold G.D. Bödeker

412
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Industrial Bioprocesses for the Production of Substituted Aromatic Heterocycles

Rainer Glöckler, Jean-Paul Roduit

413
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The Use of Hybrid Modelling for the Optimization of the Penicillin Fermentation Process

Hans Preusting, Johan Noordover, Rimvydas Simutis, Andreas Lübbert

416
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Biocatalytic vs. Chemical Synthesis of Enantiomerically Pure Compounds

Roger A. Sheldon

418
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Biocatalysis in Organic Media by Cutinase Immobilized in Reversed Micelles and Zeolites

Joaquim M.S. Cabral, Raquel M. Aires-Barros

420
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Membrane Chromatography: Performance and Scale-up

Klaus H. Gebauer, Jörg Thömmes, Maria-Regina Kula

422
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Cross-Linked Enzyme Crystals as Novel Materials for Catalysis and Chromatography

Alexey L. Margolin

423
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Regeneration of Redox Enzymes for Continuous Preparative Processes

Wim A.C. Somers, Edwin C.A. Stigter, Wim van Hartingsveldt, Jan Pieter van der Lugt

424
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Choice of a Method for in situ Recovery of 3-Pyridylacetic Acid Formed by Biotransformation with Pseudomonas oleovorans

André Jaquet, Ian W. Marison, Hans-Peter Meyer, Urs von Stockar

426
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Biocatalysis in Organic Solvents for the Production of Fine Chemicals and Specialty Polymers

Joseph O. Rich, Ping Wang, Brett D. Martin, Nitin Patil, Maria V. Sergueeva, Jonathan S. Dordick

428
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Importance of Natural Chemical Resources in Drug Discovery

Louis J. Nisbet

429
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Rational Enzyme Design: Computer Modeling and Site-directed Mutagenesis for the Modification of Catalytic Specificity in Organophosphorus Hydrolase

Kaihua Lai, Janet K. Grimsley, Barbara D. Kuhlmann, Leonardo Scapozza, Steven P. Harvey, Joseph J. DeFrank, Jan E. Kolakowski, James R. Wild

430
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Biocatalysis and Process Integration in the Synthesis of Semi-synthetic Antibiotics

Alle Bruggink

431
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Improvement of Cytochrome-P450-Mediated Biotransformations by Filamentous Fungi

Robert F.M. van Gorcom, J.M. (Hans) van den Brink, Cees A.M.J.J. van den Hondel

433
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Stereochemistry of Enzymatic Hydrolysis of Nitriles

Hiromichi Ohta

434
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Enantioselective Oxidation by Non-Heme Iron Monooxygenases from Pseudomonas

Marcel G. Wubbolts, Sven Panke, Jan B. van Beilen, Bernard Witholt

436
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Fine Chemicals and Biotechnology: The Business and the Markets

Michael S. Barber

438
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Biotechnology: Responding to the Fine Chemical Market Challenge

Stephen C. Taylor

439
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Fine Chemicals and Biotechnology: How Do Regulatory Aspects Influence the Business and Technology?

Dieter Brauer

440
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Toll Fermentation Considerations

Richard I. Mateles

441
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Cost Analysis of Fermentation Processes

Leo Hepner

442
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Leading Articles on the Occasion of the CHIMIA Anniversary 1996

Chemie – von der Alchemie zur Aschenbrödel-Wissenschaft

Hans Jucker

444
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Neue Reaktionen für die kombinatorische Chemie

Oliver Lack, Lutz Weber

445
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Community News

Results of the Competition for Students and Gymnasium (College) Classes / Information

448
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CHIMIA Report/Company News

CHIMIA-Report Companies present themselves and their products

A460
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